Accurate proteome-wide missense variant effect prediction with AlphaMissense
Por um escritor misterioso
Last updated 15 fevereiro 2025
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://www.science.org/cms/10.1126/science.adg7492/asset/e028b855-19a9-40ab-a39f-759afedb5b22/assets/images/large/science.adg7492-fa.jpg)
A catalogue of genetic mutations to help pinpoint the cause of diseases - Google DeepMind
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://www.researchgate.net/publication/370182975/figure/fig4/AS:11431281152867632@1682189657941/Combining-AlphScore-and-established-prediction-scores-improves-the-prediction-of-ClinVar.jpg)
Combining AlphScore and established prediction scores improves the
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://www.researchgate.net/publication/372959867/figure/fig1/AS:11431281180001895@1691461374305/Method-overview-We-develop-computational-missense-variant-effect-predictors-by-training.png)
Method overview. We develop computational missense variant effect
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://www.biorxiv.org/content/biorxiv/early/2023/10/13/2023.10.03.560758/F1.large.jpg)
Accurate prediction of protein tertiary structural changes induced by single-site mutations with equivariant graph neural networks
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://www.researchgate.net/publication/373047236/figure/fig5/AS:11431281192637105@1695783406803/ESM1b-can-detect-isoform-specific-variant-effects-a-Approximately-18-million-missense.png)
ESM1b can detect isoform-specific variant effects a, Approximately 1.8
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://www.researchgate.net/publication/370182975/figure/fig3/AS:11431281152867631@1682189657879/Combining-AlphScore-with-established-missense-prediction-scores-improves-correlation-with.jpg)
Combining AlphScore with established missense prediction scores
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://invivobiosystems.com/wp-content/uploads/2023/10/Five-Genes-for-Bioinformatics-in-VUS.png)
How Gene Data Sheds Light on Epilipesy
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://d3i71xaburhd42.cloudfront.net/33e49f73560e8625bd73f81bffc101c4939be95d/10-Figure7-1.png)
Can Predicted Protein 3D Structures Provide Reliable Insights into whether Missense Variants Are Disease Associated?
Jose Luis Torres Cuadros on LinkedIn: Accurate proteome-wide missense variant effect prediction with…
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://static.independent.co.uk/2023/05/04/10/deepmind%20human%20level%20ai.jpg)
Google AI breakthrough represents huge step in finding genes that cause diseases, scientists say
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://curiocial.com/content/images/2023/09/alphamissense-variant-prediction.png)
AlphaMissense's Role in Disease Diagnosis and Treatment
![Accurate proteome-wide missense variant effect prediction with AlphaMissense](https://i.gzn.jp/img/2023/09/20/google-deepmind-alphamissense/snap6059.png)
Google DeepMind announces AI ``AlphaMissense'', which may help predict which genetic mutations are harmful and identify the cause of genetic diseases - GIGAZINE
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