Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.
Por um escritor misterioso
Last updated 06 fevereiro 2025
A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.science.org/cms/10.1126/sciadv.abj9670/asset/11f20f87-1318-49f2-9b93-2f72cd11494c/assets/images/large/sciadv.abj9670-f6.jpg)
Subcellular organization of viral particles during maturation of nucleus-forming jumbo phage
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.cell.com/cms/attachment/70d089de-c79b-4112-9b1a-787938ac31d7/gr1b1.jpg)
Type III CRISPR-Cas Immunity: Major Differences Brushed Aside: Trends in Microbiology
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.biorxiv.org/content/biorxiv/early/2019/09/25/782524/F2.large.jpg?download=true)
A nucleus-forming jumbophage evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41564-020-00822-7/MediaObjects/41564_2020_822_Fig1_HTML.png)
The Rcs stress response inversely controls surface and CRISPR–Cas adaptive immunity to discriminate plasmids and phages
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://iiif.elifesciences.org/lax/45393%2Felife-45393-fig3-v1.tif/full/,1500/0/default.jpg)
A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://journals.asm.org/cms/10.1128/jb.00362-20/asset/9e7eb0d5-70eb-4a75-8523-1fc3f98e5ef3/assets/graphic/jb.00362-20-f0002.jpeg)
Intracellular Organization by Jumbo Bacteriophages
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://ars.els-cdn.com/content/image/1-s2.0-S2211124722009925-gr1.jpg)
A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli - ScienceDirect
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.biorxiv.org/content/biorxiv/early/2022/06/20/2022.06.20.496707/F6.large.jpg)
Type III CRISPR–Cas provides resistance against nucleus-forming jumbo phages via abortive infection
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://pub.mdpi-res.com/ijms/ijms-24-04363/article_deploy/html/images/ijms-24-04363-g002.png?1677483846)
IJMS, Free Full-Text
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.biorxiv.org/content/biorxiv/early/2021/03/02/2021.03.02.433402/F1.large.jpg)
Genomic characterization of four novel bacteriophages infecting the clinical pathogen Klebsiella pneumoniae
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.researchgate.net/publication/337846647/figure/fig3/AS:834427538116615@1575954436885/Phage-PHKZ-resists-Paeruginosa-type-I-C-and-type-I-F-CRISPR-Cas-immunity-a-Strain-PAO1_Q320.jpg)
Type III RNA targeting provides protection against jumbo phage
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://www.researchgate.net/profile/Susie-Warring/publication/336064267/figure/fig2/AS:807403658424320@1569511441118/The-jumbophage-assembles-a-DNA-containing-protein-shell-during-infection-that_Q320.jpg)
Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.
![Jumbophage PCH45 evades type I, but not type III, CRISPR-Cas immunity.](https://pubs.acs.org/cms/10.1021/acs.biochem.0c00273/asset/images/large/bi0c00273_0001.jpeg)
A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems
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