Advanced Quantitative Fluorescence Microscopy to Probe the Molecular Dynamics of Viral Entry, Science Lab

Viral entry into the host cell requires the coordination of many cellular and viral proteins in a precise order. Modern microscopy techniques are now allowing researchers to investigate these interactions with higher spatiotemporal resolution than ever before. Here we present two examples from the field of HIV research that make use of an innovative quantitative imaging approach as well as cutting edge fluorescence lifetime-based confocal microscopy methods to gain novel insights into how HIV fuses to cell membranes and enters the cell.

Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry

Molecular and Immunological Diagnostic Tests of COVID-19: Current Status and Challenges - ScienceDirect

Measurement Assurance for Quantitative Cell Imaging by Optical Microscopy

Understanding Virus Structure and Dynamics through Molecular Simulations

A comparison of conventional and advanced electroanalytical methods to detect SARS-CoV-2 virus: A concise review - ScienceDirect

Frontiers Molecular dynamics simulation of an entire cell

Beyond mass spectrometry, the next step in proteomics

Altered host protease determinants for SARS-CoV-2 Omicron

Microscopy in Virology, Science Lab

Natural Product Chemistry

Quantum dot as probe for disease diagnosis and monitoring - Mukherjee - 2016 - Biotechnology Journal - Wiley Online Library

Viruses, Free Full-Text

Quantitative description of a contractile macromolecular machine