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Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

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Last updated 29 dezembro 2024
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
DL001 is an FKBP12-dependent mTORC1 inhibitor. a Decreased protein
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
DL001 selectively inhibits mTORC1 in vivo. a–d Protein lysates were
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Phospho-p70 S6 Kinase (Thr389) (108D2) Rabbit mAb
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
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Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
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Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Generation and validation of the Ctns knockout rat model. (A)
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
ATP6V1B2 (D2F9R) Rabbit mAb
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Dietary supplementation of cystinotic mice by lysine inhibits the megalin pathway and decreases kidney cystine content
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