Using origami DNA to trap large viruses

A team of researchers from the Technical University of Munich and the University of Regensburg, both in Germany, has found that it is possible to build origami DNA structures that can be used to trap large viruses. In their paper published in the journal Cell Reports Physical Science, the group describes how they built their structures and how well they worked when tested.

Hollow DNA Nano-Objects Could Trap Viruses, Rendering Them Harmless

DNA Origami: From Molecular Folding Art to Drug Delivery Technology - Jiang - Advanced Materials - Wiley Online Library

Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales

The virus trap

Introducing DNA Origami

DNA Origami: From Molecular Folding Art to Drug Delivery Technology - Jiang - Advanced Materials - Wiley Online Library

Origami DNA Traps Could Keep Large Viruses From Infecting Cells: by engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

Orientation-locked DNA origami for stable trapping of small proteins in the NEOtrap

Origami DNA Traps Could Keep Large Viruses From Infecting Cells: by engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

Antigen-Triggered Logic-Gating of DNA Nanodevices

Neutralising viruses with DNA origami traps

Automated design of 3D DNA origami with non-rasterized 2D curvature

Broad-Spectrum Virus Trapping with Heparan Sulfate-Modified DNA Origami Shells

Multi-micron crisscross structures grown from DNA-origami slats

DNA Origami: Recent Progress and Applications