TropicalMed, Free Full-Text
Por um escritor misterioso
Last updated 26 junho 2024
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Chikungunya virus (CHIKV) is vectored by Aedes aegypti and Aedes albopictus mosquitoes and is found throughout tropical and sub-tropical regions. While most infections cause mild symptoms such as fever and arthralgia, there have been cases in which cardiac involvement has been reported. In adults, case reports include symptoms ranging from tachycardia and arrythmia, to myocarditis and cardiac arrest. In children, case reports describe symptoms such as arrythmia, myocarditis, and heart failure. Case reports of perinatal and neonatal CHIKV infections have also described cardiovascular compromise, including myocardial hypertrophy, ventricular dysfunction, myocarditis, and death. Myocarditis refers to inflammation of the heart tissue, which can be caused by viral infection, thus becoming viral myocarditis. Since viral myocarditis is linked as a causative factor of other cardiomyopathies, including dilated cardiomyopathy, in which the heart muscle weakens and fails to pump blood properly, the connection between CHIKV and the heart is concerning. We searched Pubmed, Embase, LILACS, and Google Scholar to identify case reports of CHIKV infections where cardiac symptoms were reported. We utilized NCBI Virus and NCBI Nucleotide to explore the lineage/evolution of strains associated with these outbreaks. Statistical analysis was performed to identify which clinical features were associated with death. Phylogenetic analysis determined that CHIKV infections with cardiac symptoms are associated with the Asian, the East Central South African, and the Indian Ocean lineages. Of patients admitted to hospital, death rates ranged from 26–48%. Myocarditis, hypertension, pre-existing conditions, and the development of heart failure were significantly correlated with death. As such, clinicians should be aware in their treatment and follow-up of patients.
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Jessore Bangladesh Historical Climate Data - Colaboratory
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TropicalMed, Free Full-Text
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Gomi Volume Ladder Download - Colaboratory
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TropicalMed, Free Full-Text
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Full article: The silent threat: asymptomatic parasitemia and malaria transmission
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Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality - ScienceDirect
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Extraordinary parasite multiplication rates in human malaria infections: Trends in Parasitology
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Download the SPHTM Fact Sheet Tulane School of Public Health and Tropical Medicine
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Frontiers Traditional Knowledge to Contemporary Medication in the Treatment of Infectious Disease Dengue: A Review
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Promoting synergies between clinical medicine and public health - Maher - 2016 - Tropical Medicine & International Health - Wiley Online Library
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Map Trong Half Life 1.1 - Colaboratory
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Full article: The silent threat: asymptomatic parasitemia and malaria transmission
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