Single-dose therapeutic interfering particle lowers SARS-CoV-2 pathogenesis and shedding among hamsters

Researchers reported that a single-dose therapeutic interfering particle (TIP) lowers SARS-CoV-2 pathogenesis and shedding among hamsters.

Hamster models of COVID-19 pneumonia reviewed: How human can they be? - Achim D. Gruber, Theresa C. Firsching, Jakob Trimpert, Kristina Dietert, 2022

Recent advances in developing small-molecule inhibitors against SARS-CoV-2 - ScienceDirect

SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2'and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to-cell fusion

COVID-19 convalescent plasma and randomized clinical trials: explaining conflicting outcomes and finding signals of efficacy

A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters

In This Issue

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

SARS-CoV-2 viral load and shedding kinetics

A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters

Frontiers Experimental Models of COVID-19

Pathogens, Free Full-Text

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Xinyue Chen - Postdoctoral Researcher - Gladstone Institutes

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Knowledge from human relevant cell, tissue and mathematics-based methods as key tools for understanding COVID-19, Book