PDF] Hybrid Diffuse Reflectance Spectroscopy: Non-Erythemal in vivo Testing of Sun Protection Factor
Por um escritor misterioso
Last updated 18 junho 2024
For the first time a robust alternative test method of SPF- and UVA-PF values is described, taking into account the interaction of sunscreen formulation and skin, and due to the elimination of any erythemal relevant UVB and U VA doses, absolutely no skin reaction occurs. Background/Aims: In order to define a label sun protection factor (SPF) of topically applied sunscreens, in vivo test methods like ISO 24444, FDA guideline, or the Australian standard are used worldwide. The basis of all these methods is provoking an erythemal skin reaction by UV irradiation to find the level of unprotected and protected minimal erythemal doses (MED). In vitro methods replacing the human skin by any kind of non-human material are still not available. Thus, offering the new hybrid diffuse reflectance spectroscopy (HDRS) technique that is able to stay on an in vivo level for SPF testing but meanwhile neglecting the UV-dose-related erythemal skin reaction is a perfect combination to take care of sun protection and any ethical concerns in SPF testing nowadays. Methods: HDRS is a combination of in vivo diffuse reflectance spectroscopy (DRS) measurements on the skin and in vitro transmission measurements of a sunscreen on a roughened polymethylmethacrylate plate. By this technique, the in vivo behavior of the investigated sunscreen on the skin is measured as well as the UVB absorption, which is still non-visible in the reflectance technique. In order to establish an alternative method for in vivo SPF testing, a huge number of sunscreens (80 samples) was measured by HDRS and compared to the worldwide accepted standard ISO 24444. The variety of sunscreens measured reflects a wide range of different types of formulations as well as a wide range of SPFs (5–120) to validate this new alternative SPF testing procedure. Results: The applied quantity of product as well as skin color dependencies of signal generation are shown to support any basic correlation of DRS signal generation and sun protection expectations. Far-reaching statistical data analyses show an excellent link of the new non-erythemally driven HDRS-SPF technique and ISO 24444 results. In the same way, HDRS-UVA-PF results can be correlated with UVA-PF values calculated from ISO 24443. Conclusion: Due to the elimination of any erythemal relevant UVB and UVA doses, absolutely no skin reaction occurs. Consequently there is no need to define a MED any more. For the first time an alternative way to SPF is shown without any ethical concerns of SPF testing in vivo and/or any restriction of SPF testing in vitro. Regardless of the type of formulation or the level of protection, an excellent correlation of SPFHDRS and SPF24444 for sunscreen labeling could be found. By this new alternative non-erythemal technique, not only SPF values can be measured, but also UVA-PF values can be calculated with an excellent correlation to ISO 24443 from the same set of data. For the first time a robust alternative test method of SPF- and UVA-PF values is described, taking into account the interaction of sunscreen formulation and skin.
Hybrid Diffuse Reflectance Spectroscopy for Non-Erythemal In-Vivo SPF Testing
Model SPF-290AS Automated UV Transmittance / SPF Analyzer - Solarlight
PDF] Hybrid Diffuse Reflectance Spectroscopy: Non-Erythemal in vivo Testing of Sun Protection Factor
Multicenter methodology comparison of the FDA and ISO standard for measurement of in vitro UVA protection of sunscreen products - ScienceDirect
PDF) In vitro measurement of sun protection factor of sunscreens by diffuse transmittance
Evaluating sunscreen ultraviolet protection using a polychromatic diffuse reflectance device - Cole - 2019 - Photodermatology, Photoimmunology & Photomedicine - Wiley Online Library
Hybrid Diffuse Reflectance Spectroscopy: Non-Erythemal in vivo Testing of Sun Protection Factor - Document - Gale OneFile: Health and Medicine
Sunscreen products: Rationale for use, formulation development and regulatory considerations. - Abstract - Europe PMC
PDF) Optics of sunscreen lotions: Preliminary results on scattering and absorption coefficients
EP1291640A1 - In vitro test method to assess the UVA protection performance of sun care products - Google Patents
PDF] Hybrid Diffuse Reflectance Spectroscopy: Non-Erythemal in vivo Testing of Sun Protection Factor
2 (5 cm) Round Beam 1000W UVB Solar Simulator Model LS1000-2R-UVB - Solarlight
PDF) Non‐invasive measurement of the 308 nm‐LED based UVB protection factor of sunscreens
Recomendado para você
-
Vivo X90 and MediaTek Dimensity 9200 fail to outperform the A16 Bionic in a real-world gaming test - News18 junho 2024
-
Vivo V23 5G Photography Test: A Promising Set of Shooters18 junho 2024
-
What is an In Vivo Test?18 junho 2024
-
In vivo efficacy testing Clinisciences18 junho 2024
-
Vivo Y3 / Y11 Test Point - Taunggyi Mobile Family18 junho 2024
-
Vivo NEX Battery Test: Remarkable Battery Life With Fast Charging Support18 junho 2024
-
in Vivo vs in Vitro Testing - What's The Difference?18 junho 2024
-
Dimensity 9300, 16 GB RAM and 1 TB storage: Vivo X100 in the performance test!18 junho 2024
-
IVISense GFR 680 Fluorescent Probe (GFR-Vivo)18 junho 2024
-
Xanon Team - Vivo y90 test point 😍😍18 junho 2024
você pode gostar
-
Mahou Shoujo of the End #4 - Vol. 4 (Issue)18 junho 2024
-
Sleeping Dogs: Definitive Edition, PC Steam Jogo18 junho 2024
-
foto de perfil sonic meme|Pesquisa do TikTok18 junho 2024
-
Final Fantasy XIV guide: List of playable races18 junho 2024
-
Mequinho (enxadrista) e Reyes (futebolista) - PICRYL - Public Domain Media Search Engine Public Domain Search18 junho 2024
-
Grand Theft Auto Liberty City Stories PC Edition Final Version 1.0 is available for download : r/pcgaming18 junho 2024
-
New Need for Speed confirmed for launch before April 202318 junho 2024
-
Genshin Impact - Materiais de Ascensão de Anemo Traveler18 junho 2024
-
For Google Play, dominating the Android ecosystem was 'existential18 junho 2024
-
OneTV Asia Mobile – Apps on Google Play18 junho 2024