Molecules, Free Full-Text
Por um escritor misterioso
Last updated 01 janeiro 2025
Extracellular vesicles (EVs), including exosomes, have an important role thanks to their ability to communicate and exchange information between tumor cells and the tumor microenvironment (TME), and have also been associated with communicating anti-cancer drug resistance (DR). The increase in proliferation of cancer cells alters oxygen levels, which causes hypoxia and results in a release of exosomes by the cancer cells. In this review, the results of studies examining the role of exosomal miRNA in DR, and their mechanism, are discussed in detail in hematological tumors: leukemia, lymphoma, and multiple myeloma. In conclusion, we underline the exosome’s function as a possible drug delivery vehicle by understanding its cargo. Engineered exosomes can be used to be more specific for personalized therapy.
Chemical Formula of Common Compounds,Chemical reaction,Molecular Formula
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Extracellular vesicles remodel tumor environment for cancer immunotherapy, Molecular Cancer
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Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Journal
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Molecules An Open Access Journal from MDPI
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Molecules An Open Access Journal from MDPI
Molecules An Open Access Journal from MDPI
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Molecules An Open Access Journal from MDPI
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