Marine Drugs, Free Full-Text

In many African countries, the Bayoud is a common disease spread involving the fungus Fusarium oxusporum f. sp. albedinis (Foa). The induction of plant natural defenses through the use of seaweed polysaccharides to help plants against pathogens is currently a biological and ecological approach that is gaining more and more importance. In the present study, we used alginate, a natural polysaccharide extracted from a brown algae Bifurcaria bifurcata, to activate date palm defenses, which involve phenylalanine ammonia-lyase (PAL), a key enzyme of phenylpropanoid metabolism. The results obtained showed that at low concentration (1 g·L−1), alginate stimulated PAL activity in date palm roots 5 times more compared to the negative control (water-treated) after 24 h following treatment and 2.5 times more compared to the laminarin used as a positive stimulator of plant natural defenses (positive control of induction). Using qRT-PCR, the expression of a selection of genes involved in three different levels of defense mechanisms known to be involved in response to biotic stresses were investigated. The results showed that, generally, the PAL gene tested and the genes encoding enzymes involved in early oxidative events (SOD and LOX) were overexpressed in the alginate-treated plants compared to their levels in the positive and negative controls. POD and PR protein genes selected encoding β-(1,3)-glucanases and chitinases in this study did not show any significant difference between treatments; suggesting that other genes encoding POD and PR proteins that were not selected may be involved. After 17 weeks following the inoculation of the plants with the pathogen Foa, treatment with alginate reduced the mortality rate by up to 80% compared to the rate in control plants (non-elicited) and plants pretreated with laminarin, which agrees with the induction of defense gene expression and the stimulation of natural defenses in date palm with alginate after 24 h. These results open promising prospects for the use of alginate in agriculture as an inducer that triggers immunity of plants against telluric pathogens in general and of date palm against Fusarium oxysporum f. sp. albedinis in particular.

The Sixth Extinction: An Unnatural History: Kolbert, Elizabeth: 9780805092998: : Books

Fuzzy Drug Targets: Disordered Proteins in the Drug-Discovery Realm

PDF) marine drugs Marine Natural Products: A Source of Novel Anticancer Drugs

Marine Drugs Referencing Guide · Marine Drugs citation (updated Nov 27 2023) · Citationsy

The best non-fiction books of all time - Pan Macmillan

PMC User Guide - PMC

Can a Jellyfish Unlock the Secret of Immortality? - The New York Times

Luxuryrentalcenter 1, Bill's Marine Service

PDF] Drugs from the deep: marine natural products as drug candidates.

Marine Drugs, Free Full-Text

Marine Drugs, Free Full-Text

Frontiers Anticancer potential of Spirastrella pachyspira (marine sponge) against SK-BR-3 human breast cancer cell line and in silico analysis of its bioactive molecule sphingosine

New Modalities for Challenging Targets in Drug Discovery - Valeur - 2017 - Angewandte Chemie International Edition - Wiley Online Library

Pharmacology of Heparin and Related Drugs: An Update