Life, Free Full-Text

More research is being conducted on myocardial cell treatments utilizing stem cell lines that can develop into cardiomyocytes. All of the forms of cardiac illnesses have shown to be quite amenable to treatments using embryonic (ESCs) and induced pluripotent stem cells (iPSCs). In the present study, we reviewed the differentiation of these cell types into cardiomyocytes from an epigenetic standpoint. We also provided a miRNA network that is devoted to the epigenetic commitment of stem cells toward cardiomyocyte cells and related diseases, such as congenital heart defects, comprehensively. Histone acetylation, methylation, DNA alterations, N6-methyladenosine (m6a) RNA methylation, and cardiac mitochondrial mutations are explored as potential tools for precise stem cell differentiation.

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𝗝𝘂𝗽𝗶𝘁𝗲𝗿 𝗘𝗱𝗴𝗲 𝗖𝗦𝗕 𝗕𝗮𝗻𝗸 𝗥𝘂𝗣𝗮𝘆 𝗟𝗶𝗳𝗲 𝗧𝗶𝗺𝗲 𝗙𝗿𝗲𝗲 𝗖𝗿𝗲𝗱𝗶𝘁 𝗖𝗮𝗿𝗱 𝗙𝘂𝗹𝗹 𝗗𝗲𝘁𝗮𝗶𝗹𝘀 & 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗣𝗿𝗼𝗰𝗲𝘀𝘀 - Features - Jupiter Community

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Life, Free Full-Text

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