IJMS, Free Full-Text
Por um escritor misterioso
Last updated 01 junho 2024
Uterine fibroids (UFs) are monoclonal, benign tumors that contain abnormal smooth muscle cells and the accumulation of extracellular matrix (ECM). Although benign, UFs are a major source of gynecologic and reproductive dysfunction, ranging from menorrhagia and pelvic pain to infertility, recurrent miscarriage, and preterm labor. Many risk factors are involved in the pathogenesis of UFs via genetic and epigenetic mechanisms. The latter involving DNA methylation and demethylation reactions provide specific DNA methylation patterns that regulate gene expression. Active DNA demethylation reactions mediated by ten-eleven translocation proteins (TETs) and elevated levels of 5-hydroxymethylcytosine have been suggested to be involved in UF formation. This review paper summarizes the main findings regarding the function of TET enzymes and their activity dysregulation that may trigger the development of UFs. Understanding the role that epigenetics plays in the pathogenesis of UFs may possibly lead to a new type of pharmacological fertility-sparing treatment method.
Ijms Free Full Text Neural And Hormonal Basis Of 49680
IJMS, Free Full-Text
IJMS Free Full-Text Research Advances In Mechanical, 52% OFF
IJMS Free Full-Text Therapeutic Potential Of Repeated, 59% OFF
Ijms Free Full Text Approaching Sex Differences In Cardiovascular
Ijms Free Full Text The Macrophages Microbiota Interplay In Irasutoya
IJMS, Free Full-Text
Ijms Free Full Text Abnormalities In Alternative 25056
IJMS, Free Full-Text
IJMS, Free Full-Text
Ijms Free Full Text Delayed Onset Of Age Dependent Changes In Ultrastructure Of Myocardial 116100
Recomendado para você
-
Rádiofobia Classics – Podcast – Podtail01 junho 2024
-
Roqueiro brasileiro que morreu em maio de 2017 Respostas01 junho 2024
-
Morre Serguei, o roqueiro brasileiro mais velho que o rock, aos 8501 junho 2024
-
Nasi – Wikipédia, a enciclopédia livre01 junho 2024
-
Chris Cornell, vocalista do Soundgarden e do Audioslave, morre nos01 junho 2024
-
Paula Toller retorna a Goiânia com a turnê Amorosa01 junho 2024
-
Morre roqueiro francês Johnny Hallyday, Música01 junho 2024
-
Serguei morre aos 85 anos; veja FOTOS, Música01 junho 2024
-
Douglas Matera: um olhar além da raia, by parapraler01 junho 2024
-
Brad Pitt vai ajudar viúva de Chris Cornell a produzir doc sobre o01 junho 2024
você pode gostar
-
Pink Piano - Apps on Google Play01 junho 2024
-
Which hated anime character is actually hot or cute? - Quora01 junho 2024
-
The Starfield tech breakdown: why it runs at 30 frames per second01 junho 2024
-
how to super in sonic ultimate rpg|TikTok Search01 junho 2024
-
Mini Massageador pistola facial Gun fitness fisioterápico sem fio 4 ponteiras - RBX - Massagem e Relaxamento - Magazine Luiza01 junho 2024
-
Losnger Men's Roar Song The Katy Perry T Shirt XL : : Clothing, Shoes & Accessories01 junho 2024
-
Light Fruit ✨ Inspired - Anime Fighting Simulator - Roblox01 junho 2024
-
França na Copa do Mundo 2022: os convocados, destaques, dias e horários dos jogos - Lance!01 junho 2024
-
Trancas bebe01 junho 2024
-
OpenTable: A New Reservation Every Two Seconds - Digital Innovation and Transformation01 junho 2024