Membrane Composition and Raf[CRD]-Membrane Attachment Are

A “Tug of War” Maintains a Dynamic Protein–Membrane Complex: Molecular Dynamics Simulations of C-Raf RBD-CRD Bound to K-Ras4B at an Anionic Membrane

Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability

Tug of war between K-Ras4B and C-Raf CRD membrane interactions. (a)

RCSB PDB - 6PTS: NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A)

Evaluation of K-Ras4B dimer interfaces and the role of Raf effectors

Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane

a) Schematic orientation states of RAS, which have different exposures

Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability

Distance of salt bridges between D154 and R161 for the K-Ras4B dimer on

Biomolecules, Free Full-Text

Cryo-EM structure of a RAS/RAF recruitment complex

Structural and mutational analyses of the role of linker residues

PDF) Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability

Biomolecules, Free Full-Text

Ras isoform-specific expression, chromatin accessibility, and signaling