Cancers, Free Full-Text

Imatinib became the standard treatment for chronic myeloid leukemia (CML) about 20 years ago, which was a major breakthrough in stabilizing the pathology and improving the quality of life of patients. However, the emergence of resistance to imatinib and other tyrosine kinase inhibitors leads researchers to characterize new therapeutic targets. Several studies have highlighted the role of histone deacetylase 6 (HDAC6) in various pathologies, including cancer. This protein effectively intervenes in cellular activities by its primarily cytoplasmic localization. In this review, we will discuss the molecular characteristics of the HDAC6 protein, as well as its overexpression in CML leukemic stem cells, which make it a promising therapeutic target for the treatment of CML.

100% Cancer Free sticker — Perch Handmade

Institutional Repository LinkOut: A New Full Text Access Feature in PubMed. NLM Technical Bulletin. 2017 Mar–Apr

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Kidney Cancer: Symptoms, Signs, Causes & Treatment

Kidney Cancer Text · Free Stock Photo

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

IASLC International Association for the Study of Lung Cancer

Free PSD Breast cancer awareness editable text effect

Destination Healthy Skin Toolkit - The Skin Cancer Foundation

Download or order free information booklets

Cancer Anniversary

Quantitative estimates of preventable and treatable deaths from 36 cancers worldwide: a population-based study - The Lancet Global Health

Oxidative stress, inflammation, and cancer: How are they linked? - ScienceDirect

Home Page: Lung Cancer

Cancers, Free Full-Text